AN INNOVATIVE PHASE 2 CHRONIC PAIN MASTER PROTOCOL DESIGN TO ASSESS NOVEL MECHANISMS IN MULTIPLE PAIN TYPES

Abstract.Introduction:.The phase 2 chronic pain master protocol (CPMP) presented here provides a construct to accelerate the Heart Rate Wire Harness investigation of novel analgesics, broadly referred to here as mechanisms.Designed to address historical challenges in analgesic research and development, such as the choice of indication, this protoco

Sour rot (SR) is a disease complex that affects grape Pad berries during ripening and can cause severe yield losses and deterioration of wine quality.The etiology and epidemiology of the disease remain uncertain, which has severely limited the development of specific, targeted management strategies.In this study, a network meta-analysis was applied